Apheresis and photopheresis
Norton Children’s Cancer Institute features the region’s only pediatric apheresis and photopheresis program.
Apheresis and photopheresis are used to treat leukemia and sickle cell disease. Apheresis and photopheresis also fight graft-versus-host disease after bone marrow transplants and rejection after organ transplants.
Medical apheresis is a taking away of specific blood components from a donor (patient) by a special machine that can differentiate these components.
The type of apheresis depends on which component is being taken away during the procedure:
- Red blood cell exchange is an effective therapy for sickle cell disease in which damaged red cells are removed and replaced with healthy red blood cells.
- White cell depletion uses apheresis to remove white blood cells when levels are dangerously high.
- Red blood cell depletion removes excess red blood cells using apheresis.
- With photopheresis, white blood cells are treated with an ultraviolet light-activated photoactive drug before being returned to the patient’s blood. This is used to treat graft-versus-host disease, organ rejection in solid organ transplants, Crohn’s disease and ulcerative colitis.
- Plasmapheresis replaces blood plasma with plasma from a healthy donor. It is used to treat conditions such as thrombotic thrombocytopenic purpura or organ rejection after a transplant.
Advanced pediatric cancer care that isn’t too far from home.
When a pediatrician suspects a child has a serious heart issue, the physician and parents want to understand the situation quickly with a speedy diagnosis. If families in Kentucky or Indiana had to drive to […]Read Full Story
The Kentucky Poison Control Center of Norton Children’s Hospital has been working to reduce illness and death from poisoning in Kentucky for 65 years. The center provides 24/7 free and confidential access to specially trained […]Read Full Story
Nearly half of women who die by homicide in the U.S. are killed by a current or former intimate partner. Now a new study in JAMA Pediatrics shows that adolescent girls are at risk for […]Read Full Story