Brain Tumor Clinical Trials, Studies and Research

Norton Children’s Cancer Institute, affiliated with the UofL School of Medicine, is at the forefront of pediatric brain tumor treatment research. As investigators on numerous trials, our specialist physicians have unparalleled experience with many innovative treatments once they are approved for broad use. Patients also may be eligible to take part in these experimental pediatric brain tumor treatments. Norton Children’s Cancer Institute researchers also contribute to groundbreaking studies and other publications in peer-reviewed journals.

Learn more about participating in a clinical trial at Norton Healthcare.

Current Pediatric Brain Tumor Clinical Trials and Studies

High-Grade Glioma

A Phase 2 Study of Dabrafenib (NSC# 763760) with Trametinib (NSC# 763093) after Local Irradiation in Newly Diagnosed BRAFV600-Mutant High-Grade Glioma (HGG) (IND #145355)
Study Type: Drug Study
Ashok Raj, M.D.
Ashok Raj, M.D.
Principal Investigator
Norton Children's Cancer Institute,
affiliated with the UofL School of Medicine
Sponsor: Children's Oncology Group (COG)

Low-Grade Glioma (LGG)

A Phase 3 Randomized Study of Selumetinib (IND # 77782) versus Carboplatin/Vincristine in Newly Diagnosed or Previously Untreated Neurofibromatosis Type 1 (NF1) Associated Low-Grade Glioma (LGG)
Study Type: Drug Study
Ashok Raj, M.D.
Ashok Raj, M.D.
Principal Investigator
Norton Children's Cancer Institute,
affiliated with the UofL School of Medicine
Sponsor: Children's Oncology Group (COG)

Low-Grade Glioma (LGG)

A Phase 3 Randomized Non-Inferiority Study of Carboplatin and Vincristine versus Selumetinib (NSC# 748727, IND# 77782) in Newly Diagnosed or Previously Untreated Low-Grade Glioma (LGG) not associated with BRAFV600E Mutations or Systemic Neurofibromatosis Type 1 (NF1)
Study Type: Drug Study
Ashok Raj, M.D.
Ashok Raj, M.D.
Principal Investigator
Norton Children's Cancer Institute,
affiliated with the UofL School of Medicine
Sponsor: Children's Oncology Group (COG)

Elementary students raise $40,000 for Norton Children’s Hospital

North Harrison Elementary School students raised $41,179.46 for Norton Children’s Hospital — the most the school has raised in more than 30 years of fundraisers. The Ramsey, Indiana, students raised $41,179.46 for Norton Children’s Hospital […]

Read Full Story

Teaching lawn mower safety tips can help your child avoid serious injuries

Practicing lawn mower safety Injuries involving lawn care equipment can have devastating consequences, and families should teach lawn mower safety tips to their children. Children can be injured or killed during lawn mower accidents, and […]

Read Full Story

New breakthrough drugs for cystic fibrosis are helping kids feel better

There is no cure for cystic fibrosis (CF), but breakthrough new drugs recently have been approved for children as young as 4 months, with more in the research stages that target the genetic mutations responsible [...]

Read Full Story

A minor cut or scrape can lead to septic arthritis in children

What is septic arthritis in children? Septic arthritis is a painful infection that occurs inside of a joint, including the joint fluid (synovial fluid) or surrounding joint tissues. “Septic arthritis in children is caused by […]

Read Full Story

Oído de nadador vs. infección del oído y cómo saber diferenciarlos

This story is also available in English Comprender las diferencias entre el oído del nadador y las infecciones del oído y cómo reconocerlas puede ser difícil. El dolor de oído y las infecciones son comunes […]

Read Full Story

Search our entire site.