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What is tetralogy of Fallot?

Jimmy Kimmel's newborn has a heart defect that impacts nearly 2,000 infants a year.

tetralogy fallot

Late-night TV host Jimmy Kimmel used his opening monologue Monday night to give an emotional account of how his newborn son was diagnosed with tetralogy of Fallot.

Tetralogy of Fallot (TOF) is a congenital heart condition marked by four defects: a hole in the heart; the aorta lying over the hole; an obstruction from the heart to the lungs; and a thick muscle wall. TOF limits blood flow to the rest of the body. Infants and children with the condition usually have blue-tinted skin because their blood doesn’t carry enough oxygen.

TOF is rare, but also one of the most common heart defects — about 1,660 U.S. babies are born with it each year.

With early diagnosis followed by one or multiple surgeries, most children who have TOF live relatively normal lives, though they need regular medical care an might have restrictions on exercise.

TOF is one of the many conditions treated at Norton Children’s Heart Center. Recently, Erle H. Austin III, M.D., pediatric cardiovascular surgeon with Norton Children’s Hospital and University of Louisville Physicians, helped save a young Bowling Green girl born with TOF.


Jimmy Kimmel Reveals Details of His Son’s Birth & Heart Disease

Jimmy and his wife Molly welcomed their second child together, William “Billy” Kimmel. At three days old, Billy had successful open heart surgery at Children’s Hospital Los Angeles and is now home with his family. Jimmy opens up about his son’s birth and health complications and encourages donations to Children’s Hospital Los Angeles where Billy and so many other kids get such wonderful care…


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