Hand, Foot, and Mouth Disease The coxsackievirus (say: kok-SAK-ee-vy-rus) causes this infection. Kids who have it get blisters on their hands and feet, in their mouth and throat, and sometimes on their bottom. They also can have a fever. Hand, food, and mouth disease goes away on its own without any medicine. Back to Articles Related Articles Word! Coxsackievirus A coxsackievirus is one of a group of viruses or germs that live in the digestive tract and can make you sick. Read More What Are Germs? You know they can hurt you, but what are these invisible creatures? Find out in this article for kids. Read More Blisters Ouch! What are blisters? Find out in this article for kids. Read More Note: All information is for educational purposes only. For specific medical advice, diagnoses, and treatment, consult your doctor. © 1995-2021 KidsHealth®. All rights reserved. Images provided by The Nemours Foundation, iStock, Getty Images, Veer, Shutterstock, and Clipart.com.